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Randomized Controlled Trial
. 2012 Mar 12;172(5):442-4.
doi: 10.1001/archinternmed.2011.1391.

Effect of antihypertensive therapy on cognitive function in early executive cognitive impairment: a double-blind randomized clinical trial

Ihab Hajjar, Meaghan Hart, Yu-Ling Chen, Wendy Mack, William Milberg, Helena Chui, Lewis Lipsitz
Randomized Controlled Trial

Effect of antihypertensive therapy on cognitive function in early executive cognitive impairment: a double-blind randomized clinical trial

Ihab Hajjar et al. Arch Intern Med. .
No abstract available

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Figures

Figure 1
Figure 1. Significant changes in the adjusted least square mean over study period in the three groups
Least square means were adjusted for age and baseline Mini-Mental-State-Exam. p-values are obtained from the linear mixed model for the visit by group interaction parameter. V0–V1: change from baseline to 6 months; V0–V2: change from baseline to 12 months; V1–V2: change from 6 months to 12 months. TMT: Trail Making Test. HVLT: Hopkins verbal learning test. HCTZ: hydrochlorothiazide.
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References

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    1. Hajjar I, Hart M, Milberg W, Novak V, Lipsitz L. The rationale and design of the antihypertensives and vascular, endothelial, and cognitive function (AVEC) trial in elderly hypertensives with early cognitive impairment: role of the renin angiotensin system inhibition. BMC geriatrics. 2009;9:48. - PMC - PubMed

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