[Psychopharmacology and oral psychosomatic disorder]

Abstract

It is uncommon to encounter patients presenting with medically and psychiatry unexplained oral symptoms like pain or discomfort. These symptoms have been called "oral psychosomatic disorders (OPSD)" in general. From a clinical point of view, OPSD may be due to several biochemical disorders involving neurotransmitters in the brain, incomplete connections between oral region and undefined complaints due to cognitive processes in higher centers of the brain. The main psychosomatic treatment is psychopharmacological therapy with antidepressants, including tricyclic antidepressants (TCAs), serotonin-norepinephrine reuptake inhibitors(SNRIs), selective serotonin reuptake inhibitors(SSRIs), and other antidepressants (e.g., mirtazapine)". The proper use of these antidepressants is extremely important for the successful treatment of OPSD.