Implication of new atherosclerotic carotid plaques in the cardiovascular outcome of patients with rheumatoid arthritis
- PMID: 22414597
- PMCID: PMC3446405
- DOI: 10.1186/ar3733
Implication of new atherosclerotic carotid plaques in the cardiovascular outcome of patients with rheumatoid arthritis
Abstract
Early detection of atherosclerosis is of major importance to reduce the increased incidence of cardiovascular (CV) complications observed in patients with rheumatoid arthritis (RA). Prospective studies have shown that an abnormally increased carotid intima-media thickness and the presence of plaques assessed by carotid ultrasound are good markers to predict the development of CV events in these patients. Age, classic CV risk factors, and corticosteroid use are also predictors of new plaque formation in patients with RA. Active treatment of the disease may decrease the inflammatory burden, leading to a reduction in the progression of subclinical atherosclerosis in these patients.
Comment on
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Predictors of new atherosclerotic carotid plaque development in patients with rheumatoid arthritis: a longitudinal study.Arthritis Res Ther. 2012 Mar 5;14(2):R44. doi: 10.1186/ar3757. Arthritis Res Ther. 2012. PMID: 22390577 Free PMC article.
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- Zampeli E, Protogerou A, Stamatelopoulos K, Fragiadaki K, Katsiari CG, Kyrkou K, Papamichael CM, Mavrikakis M, Nightingale P, Kitas GD, Sfikakis PP. Predictors of new atherosclerotic carotid plaque development in patients with rheumatoid arthritis: a longitudinal study. Arthritis Res Ther. 2012;14:R44. doi: 10.1186/ar3757. - DOI - PMC - PubMed
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