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Review
. 2012 Jan;8(1):75-84.
doi: 10.2174/157340612799278388.

BioArena studies: unique function of endogenous formaldehyde and ozone in the antibiotic effect--a review

Erno Tyihák  1 , Agnes M Móricz, Péter G Ott
Affiliations
Review

BioArena studies: unique function of endogenous formaldehyde and ozone in the antibiotic effect--a review

Erno Tyihák et al. Med Chem. 2012 Jan.

Abstract

The investigations demonstrated clearly a unique function and role of endogenous formaldehyde (HCHO) and ozone (O3) in the antibiotic effect of diverse molecules having different chemical structure. Elimination of HCHO and/or O3 from the layer chromatographic spots resulted in a decrease in the antimicrobial activity. On the basis of detection and measure of endogenous HCHO and O3 BioArena enables to both direct isolation and biological evaluation of new bioactive compounds.

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