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. 2012 Mar 15;11(3):219-21.
doi: 10.1016/j.chom.2012.02.004.

To die or not to die: Shigella has an answer

Thomas Rudel  1
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To die or not to die: Shigella has an answer

Thomas Rudel. Cell Host Microbe. .
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Abstract

Invasion of epithelial cells by Shigella is a critical step in the pathogenesis of bacillary dysentery. In this issue of Cell Host & Microbe, Bergounioux et al. (2012) uncover a complex interplay of proinvasion, prosurvival, and prodeath signals centered on the activation of calpain protease by the Shigella VirA protein.

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