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Comment
. 2012 Mar 15;11(3):223-5.
doi: 10.1016/j.chom.2012.02.003.

A way to DAI

Patrick-Simon Welz  1 , Manolis Pasparakis
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Free article
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A way to DAI

Patrick-Simon Welz et al. Cell Host Microbe. .
Free article

Abstract

RIP3-regulated necrosis has recently emerged as an important antiviral host defense mechanism. A new study by Upton et al. (2012) identifies DAI, a cytoplasmic DNA sensor, as a partner of RIP3 that is essential for the induction of regulated necrosis in cytomegalovirus-infected cells.

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