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Review
. 2012 May;90(5):277-83.
doi: 10.1016/j.ciresp.2011.11.006. Epub 2012 Mar 15.

[Epigenetics and colorectal cancer]

[Article in Spanish]
Pablo Menéndez  1 , Pedro Villarejo, David Padilla, José María Menéndez, José Antonio Rodríguez Montes
Affiliations
Review

[Epigenetics and colorectal cancer]

[Article in Spanish]
Pablo Menéndez et al. Cir Esp. 2012 May.

Abstract

The epigenetic and physiological mechanisms that alter the structure of chromatin include the methylation of DNA, changes in the histones, and changes in RNA. A literature review has been carried out using PubMed on the evidence published on the association between epigenetics and colorectal cancer. The scientific literature shows that epigenetic changes, such as genetic modifications may be very significant in the origin of neoplastic disease, contributing both to the development and progression of the disease.

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