Cohort Profile: the international childhood cardiovascular cohort (i3C) consortium

Abstract

This is a consortium of large children's cohorts that contain measurements of major cardiovascular disease (CVD) risk factors in childhood and had the ability to follow those cohorts into adulthood. The purpose of this consortium is to enable the pooling of data to increase power, most importantly for the follow-up of CVD events in adulthood. Within the consortium, we hope to be able to obtain data on the independent effects of childhood and early adult levels of CVD risk factors on subsequent CVD occurrence.

Figure 1

Geographical locations of the participating longitudinal cohorts in the i3C Consortium (1–7). 1: Muscatine Study, Muscatine, IA, USA; 2: BHS, Bogalusa, LA, USA; 3: five dots in Finland represent study sites in the Cardiovascular Risk in Young Finns Study, Oulu, Kuopio, Tampere, Turku and Helsinki, Finland; 4: all dots in Australia represent study sites in the CDAH Study, Hobart, Melbourne, Sydney, Canberra, Adelaide, Brisbane, Darwin, Perth, small cities and towns, Australia; 5: Minneapolis Children's Studies, Minneapolis, MN, USA; 6: Princeton LRC Study, PFS, and NGHS, Cincinnati, OH, USA; 7: NGHS, Richmond, CA, and Washington, DC, USA