Lowering plasma cholesterol by raising LDL receptors--revisited
- PMID: 22435375
- PMCID: PMC5611813
- DOI: 10.1056/NEJMe1202168
Lowering plasma cholesterol by raising LDL receptors--revisited
Comment on
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Effect of a monoclonal antibody to PCSK9 on LDL cholesterol.N Engl J Med. 2012 Mar 22;366(12):1108-18. doi: 10.1056/NEJMoa1105803. N Engl J Med. 2012. PMID: 22435370 Clinical Trial.
References
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- Mabuchi H, Haba T, Tatami R, et al. Effect of an inhibitor of 3-hydroxy-3-methyglutaryl coenzyme A reductase on serum lipoproteins and ubiquinone-10-levels in patients with familial hypercholesterolemia. N Engl J Med. 1981;305:478–82. - PubMed
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- Brown MS, Goldstein JL. Lowering plasma cholesterol by raising LDL receptors (Editorial) N Engl J Med. 1981;305:515–7. - PubMed
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- Abifadel M, Varret M, Rabes JP, et al. Mutations in PCSK9 cause autosomal dominant hypercholesterolemia. Nat Genet. 2003;34:154–6. - PubMed
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