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Editorial
. 2012 Mar 22;366(12):1154-5.
doi: 10.1056/NEJMe1202168.

Lowering plasma cholesterol by raising LDL receptors--revisited

Editorial

Lowering plasma cholesterol by raising LDL receptors--revisited

Stephen G Young et al. N Engl J Med. .
No abstract available

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Comment on

  • Effect of a monoclonal antibody to PCSK9 on LDL cholesterol.
    Stein EA, Mellis S, Yancopoulos GD, Stahl N, Logan D, Smith WB, Lisbon E, Gutierrez M, Webb C, Wu R, Du Y, Kranz T, Gasparino E, Swergold GD. Stein EA, et al. N Engl J Med. 2012 Mar 22;366(12):1108-18. doi: 10.1056/NEJMoa1105803. N Engl J Med. 2012. PMID: 22435370 Clinical Trial.

References

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    1. Lagace TA, Curtis DE, Garuti R, et al. Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and in livers of parabiotic mice. J Clin Invest. 2006;116:2995–3005. - PMC - PubMed
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