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. 2012 Feb;20(1):9-15.
doi: 10.1590/s1678-77572012000100003.

Rehabilitative treatment of cleft lip and palate: experience of the Hospital for Rehabilitation of Craniofacial Anomalies/USP (HRAC/USP)--Part 1: overall aspects

José Alberto de Souza Freitas  1 , Lucimara Teixeira das Neves, Ana Lúcia Pompéia Fraga de Almeida, Daniela Gamba Garib, Ivy Kiemle Trindade-Suedam, Renato Yassutaka Faria Yaedú, Rita de Cássia Moura Carvalho Lauris, Simone Soares, Thais Marchini Oliveira, João Henrique Nogueira Pinto
Affiliations

Rehabilitative treatment of cleft lip and palate: experience of the Hospital for Rehabilitation of Craniofacial Anomalies/USP (HRAC/USP)--Part 1: overall aspects

José Alberto de Souza Freitas et al. J Appl Oral Sci. 2012 Feb.

Abstract

Cleft lip and palate is the most common among craniofacial malformations and causes several esthetic and functional implications that require rehabilitation. This paper aims to generally describe the several aspects related to this complex pathology and the treatment protocol used by the Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo (HRAC-USP) along 40 years of experience in the treatment of individuals with cleft lip and palate.

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Figures

Figure 1
Figure 1
A and B - Complete unilateral cleft lip affecting the lip, alveolar ridge and anterior palate; C and D - Complete unilateral cleft lip and palate (affecting the lip, alveolar ridge and primary and secondary palate); E and F - Complete bilateral cleft lip and palate (affecting the lip, alveolar ridge and primary and secondary palate); G - Incomplete cleft palate (involving only the soft palate and uvula) and H - Complete cleft palate (completely involving the secondary palate)
Figure 2
Figure 2
A and B – Pre- and postoperative aspect of cheiloplasty (surgical repair of the lip); C and D – Pre- and postoperative aspect of palatoplasty (surgical repair of the palate)
See this image and copyright information in PMC

References

    1. Blanton SH, Cortez A, Stal S, Mulliken JB, Finnell RH, Hecht JT. Variation in IRF6 contributes to nonsyndromic cleft lip and palate. Am J Med Genet. 2005;137A:259–262. - PubMed
    1. Dixon MJ, Marazita ML, Beaty TH, Murray JC. Cleft lip and palate: understanding genetic and environmental influences. Nat Rev Genet. 2011;12:167–178. - PMC - PubMed
    1. Etheredge AJ, Christensen K, Del Junco D, Murray JC, Mitchell LE. Evaluation of two methods for assessing gene-environment interactions using data from the Danish case-control study of facial clefts. Birth Defects Res A Clin Mol Teratol. 2005;73:541–546. - PubMed
    1. Jezewski PA, Vieira AR, Nishimura C, Ludwig B, Johnson M, O'Brien SE, et al. Complete sequencing shows a role for MSX1 in non-syndromic cleft lip and palate. J Med Genet. 2003;40:399–407. - PMC - PubMed
    1. Jia Z, Li Y, Li L, Wu J, Zhu LY, Yang C, et al. Association among IRF6 polymorphism, environmental factors, and nonsyndromic orofacial clefts in Western China. DNA Cell Biol. 2009;28:249–257. - PubMed