T cell memory: Skin-deep memory

Comment

Lucy Bird. Nat Rev Immunol. 2012.

. 2012 Mar 22;12(4):230-1.

doi: 10.1038/nri3201.

No abstract available

Comment on

Skin effector memory T cells do not recirculate and provide immune protection in alemtuzumab-treated CTCL patients.
Clark RA, Watanabe R, Teague JE, Schlapbach C, Tawa MC, Adams N, Dorosario AA, Chaney KS, Cutler CS, Leboeuf NR, Carter JB, Fisher DC, Kupper TS. Clark RA, et al. Sci Transl Med. 2012 Jan 18;4(117):117ra7. doi: 10.1126/scitranslmed.3003008. Sci Transl Med. 2012. PMID: 22261031 Free PMC article.
Skin infection generates non-migratory memory CD8+ T(RM) cells providing global skin immunity.
Jiang X, Clark RA, Liu L, Wagers AJ, Fuhlbrigge RC, Kupper TS. Jiang X, et al. Nature. 2012 Feb 29;483(7388):227-31. doi: 10.1038/nature10851. Nature. 2012. PMID: 22388819 Free PMC article.