Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010 Jul;1(2):127-34.
doi: 10.4103/0975-5950.79214.

Prevention and management of antineoplastic therapy induced oral mucositis

Afshan Bey  1 , Syed S Ahmed, Bilal Hussain, Seema Devi, Sarwat H Hashmi
Affiliations

Prevention and management of antineoplastic therapy induced oral mucositis

Afshan Bey et al. Natl J Maxillofac Surg. 2010 Jul.

Abstract

With the scientific advancements in the management of malignant diseases, the treatment is expensive and bears high morbidity in term of oral mucositis. It is a debilitating condition and has been researched extensively for its pathogenesis and treatment. Various treatment options include barrier forming, mucosal protectants, mouth rinses, growth factors, lasers and midline-sparing procedures. Some agents are used locally while others are administered systemically. Despite the availability of a wide range of treatment options for mucositis, a cost-effective treatment is yet to be evolved.

Keywords: Antineoplastic therapy; mucosal protectants; oral mucositis.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: None declared.

References

    1. Sonis ST. Mucositis as a biological process: A new hypothesis for the development of chemotherapy-induced stomatotoxicity. Oral Oncol. 1998;34:39–43. - PubMed
    1. Knox JJ, Puodziunas AL, Feld R. Chemotherapy-induced oral mucositis: Prevention and management. Drugs Aging. 2000;17:257–67. - PubMed
    1. Woo SB, Sonis ST, Monopoli MM, Sonis AL. A longitudinal study of oral ulcerative mucositis in bone marrow transplant recipients. Cancer. 1993;72:1612–7. - PubMed
    1. Sonis ST. A biological approach to mucositis. J Support Oncol. 2004;2:21–36. - PubMed
    1. Sonis ST. The Pathobiology of Mucositis. Nat Rev Cancer. 2004;4:277–84. - PubMed