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. 1990 Nov 1;271(3):835-8.
doi: 10.1042/bj2710835.

Computer simulation of a cytosolic calcium oscillator

S Swillens  1 , D Mercan
Affiliations

Computer simulation of a cytosolic calcium oscillator

S Swillens et al. Biochem J. .

Abstract

A new interpretation of existing data permits us to define a model capable of accounting for agonist-induced Ca2+ oscillations in the cytosol of electrically non-excitable cells. The model only requires one Ca2+ store, which contains Ca2+ channels controlled by inositol 1,4,5-trisphosphate and Ca2+. Computer simulations may generate different experimentally observed patterns of Ca2+ oscillations.

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