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. 2012 Jun;56(6):3376-7.
doi: 10.1128/AAC.00313-12. Epub 2012 Mar 26.

Dissemination of pCT-like IncK plasmids harboring CTX-M-14 extended-spectrum β-lactamase among clinical Escherichia coli isolates in the United Kingdom

Hiran Dhanji  1 , Parmina Khan, Jennifer L Cottell, Laura J V Piddock, Jiancheng Zhang, David M Livermore, Neil Woodford
Affiliations

Dissemination of pCT-like IncK plasmids harboring CTX-M-14 extended-spectrum β-lactamase among clinical Escherichia coli isolates in the United Kingdom

Hiran Dhanji et al. Antimicrob Agents Chemother. 2012 Jun.

Abstract

IncK plasmids encoding CTX-M-14 extended-spectrum β-lactamase (ESBL) and highly related to plasmid pCT were detected in 13 of 67 (19%) human clinical isolates of Escherichia coli with a group 9 CTX-M-type ESBL from the United Kingdom and in 2 quality assurance isolates. None of these E. coli strains was related to the cattle strain from which pCT was originally characterized.

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Figures

Fig 1
Fig 1
Dendrogram showing the genetic relatedness based on PFGE typing among the 15 E. coli producing CTX-M-14 ESBL and harboring pCT-like plasmids and a pCT-positive E. coli isolate from cattle (GenBank accession no. F868832.1).
See this image and copyright information in PMC

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