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. 2012 Mar 27:12:2.
doi: 10.1186/1472-698X-12-2.

Provision and awareness for isoniazid preventive therapy among PLHIV in Addis Ababa, Ethiopia

Amenu Wesen  1 , Getnet Mitike
Affiliations

Provision and awareness for isoniazid preventive therapy among PLHIV in Addis Ababa, Ethiopia

Amenu Wesen et al. BMC Int Health Hum Rights. .

Abstract

Background: The risk of acquiring tuberculosis by People living with HIV (PLHIV) could significantly be reduced through provision of isoniazid preventive therapy (IPT). In Ethiopia, it is neither practiced well nor researched in depth. Our objective was to assess IPT provision and awareness among PLHIV in Addis Ababa City Administration.

Methods: Between February 2008 and May 2008, a cross sectional facility-based survey was conducted by exit interview of 406 PLHIV from six health facilities. The findings were analyzed and described in this report.

Results: The proportion of PLHIV ever had been provided with IPT were 74 of 231 TB free PLHIV (32.0%) and the proportion of having information about IPT among study participants was 29.8%. Females were about two times more informed about the provision of IPT in their health facilities than males [AOR (95%CI): 2.18 (1.31-3.61)].

Conclusions: We conclude that the practice of provision of IPT for PLHIV is high, but there is room for improvement. Provision of INH for TB free PLHIV has to be strengthened with better diagnostic facilities to certainly rule out active TB cases.

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Figures

Figure 1
Figure 1
Provision of IPT in relation to TB free people living with HIV across the health facilties, Addis Ababa City Administration, February 2008. n = 231.
See this image and copyright information in PMC

References

    1. WHO. Guidelines for the implementation of collaborative TB and HIV program activities. Geneva, Switzerland; 2003.
    1. Wilkinson D. Drugs for preventing tuberculosis in HIV infected persons. Chocrane Database Sys Rev. 2000;2:CD000171. - PubMed
    1. Pape JW, Jean SS, Hafner A, Johnson WD Jr. Effect of Isoniazid prophylaxis on incidence of active tuberculosis on HIV infection. Lancet. 1993;342(8866):268–272. doi: 10.1016/0140-6736(93)91817-6. - DOI - PubMed
    1. Fitzgerald DW, Desvarieux M, Severe P, Joseph P, Johnson WD Jr, Pape JW. Effect of post treatment isoniazid on prevention of recurrent tuberculosis in HIV -1 infected individuals: a randomized trial. Lancet. 2000;356(9240):1470–1474. doi: 10.1016/S0140-6736(00)02870-1. - DOI - PubMed
    1. Churchyard GJ, Fielding K, Charalambous S, Day JH, Corbett EL, Hayes RJ, Chaisson RE, De Cock KM, Samb B, Grant AD. Efficacy of secondary isoniazid preventive therapy among HIV-infected Southern Africans: time to change policy. AIDS. 2003;17(14):2063–2070. doi: 10.1097/00002030-200309260-00007. - DOI - PubMed

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