Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1974 Jun;1(3):271-5.
doi: 10.1111/j.1365-2125.1974.tb00249.x.

Charcoal haemoperfusion for paracetamol overdose

B G Gazzard  1 , R A Willison, M J Weston, R P Thompson, R Williams
Affiliations

Charcoal haemoperfusion for paracetamol overdose

B G Gazzard et al. Br J Clin Pharmacol. 1974 Jun.

Abstract

1 A controlled trial of charcoal haemoperfusion as an early treatment for paracetamol overdose showed no benefit. 2 The plasma clearances of paracetamol by the charcoal column were variable and disappointingly small (range 4-119 ml/minute). The cumulative amounts removed were also low, mean 1.4 g (range 0.2-5.2 g). 3 No clinical problems were encountered with the technique of haemoperfusion and in particular the drop in blood platelet counts was small (mean fall 16%).

PubMed Disclaimer

References

    1. J Pharm Pharmacol. 1973 Dec;25(12):964-7 - PubMed
    1. Lancet. 1973 Jan 13;1(7794):66-70 - PubMed
    1. Br Med J. 1973 Jul 14;3(5871):86-7 - PubMed
    1. J Clin Pathol. 1971 Sep;24(6):542-6 - PubMed
    1. Lancet. 1973 Jan 13;1(7794):77-9 - PubMed

LinkOut - more resources