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. 2012 Apr 6;14(7):1900-1.
doi: 10.1021/ol300539e. Epub 2012 Mar 28.

Preparation of trifluoromethyl-substituted aziridines with in situ generated CF3CHN2

Stefan A Künzi  1 , Bill Morandi, Erick M Carreira
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Preparation of trifluoromethyl-substituted aziridines with in situ generated CF3CHN2

Stefan A Künzi et al. Org Lett. .

Abstract

Direct access to trifluoromethyl-substituted aziridines through the use of a protocol in which trifluoromethyl diazomethane is generated in situ and subsequently undergoes addition to activated imines is reported.

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