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Randomized Controlled Trial
. 2012 Aug;222(3):519-32.
doi: 10.1007/s00213-012-2677-1. Epub 2012 Mar 29.

The effects of energy drink in combination with alcohol on performance and subjective awareness

Affiliations
Randomized Controlled Trial

The effects of energy drink in combination with alcohol on performance and subjective awareness

Chris Alford et al. Psychopharmacology (Berl). 2012 Aug.

Abstract

Rationale: This study investigated the coadministration of an energy drink with alcohol to study the effects on subjective intoxication and objective performance.

Objectives: This study aims to evaluate the objective and subjective effects of alcohol versus placebo at two alcohol doses, alone and in combination with an energy drink, in a balanced order, placebo-controlled, double-blind design.

Methods: Two groups of ten healthy volunteers, mean (SD) age of 24 (6.5), participated in the study. One group consumed energy drink containing 80 mg of caffeine and the other consumed a placebo drink, with both receiving two alcohol doses (0.046 and 0.087% breathalyser alcohol concentration). Tests included breath alcohol assessment, objective measures of performance (reaction time, word memory and Stroop task) and subjective visual analogue mood scales.

Results: Participants showed significantly impaired reaction time and memory after alcohol compared to the no alcohol condition and had poorer memory after the higher alcohol dose. Stroop performance was improved with the energy drink plus alcohol combination compared to the placebo drink plus alcohol combination. Participants felt significant subjective dose-related impairment after alcohol compared to no alcohol. Neither breath alcohol concentration nor the subjective measures showed a significant difference between the energy drink and the placebo energy drink when combined with alcohol.

Conclusions: Subjective effects reflected awareness of alcohol intoxication and sensitivity to increasing alcohol dose. There were no overall significant group differences for subjective measures between energy drink and placebo groups in the presence of alcohol and no evidence that the energy drink masked the subjective effects of alcohol at either dose.

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Figures

Fig. 1
Fig. 1
Performance results—RRT and immediate memory recall, contrasting alcohol and energy drink alone, as well as in combination, and against their respective placebos
Fig. 2
Fig. 2
Subjective awareness—clearheaded and clumsy, contrasting alcohol and energy drink alone, as well as in combination, and against their respective placebos

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