Implantable continuous-flow right ventricular assist device: lessons learned in the development of a cleveland clinic device
- PMID: 22459544
- PMCID: PMC3447008
- DOI: 10.1016/j.athoracsur.2012.02.026
Implantable continuous-flow right ventricular assist device: lessons learned in the development of a cleveland clinic device
Abstract
Although the need for right ventricular assist device (RVAD) support for right ventricular failure after the implantation of a continuous-flow left ventricular assist device has decreased, right ventricular failure still occurs in as many as 44% of patients after continuous-flow left ventricular assist device insertion. Cleveland Clinic's DexAide continuous-flow RVAD was implanted in 34 calves during the course of its development. This review discusses lessons learned in the design and development of an implantable continuous-flow RVAD that are drawn from the results of these in vivo studies, our clinical experience with RVAD support, and a review of previously published reports on clinical RVAD use.
Copyright © 2012 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
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References
-
- Slaughter MS, Rogers JG, Milano CA, et al. Advanced heart failure treated with continuous-flow left ventricular assist device. N Engl J Med. 2009;361:2241–2251. - PubMed
-
- Strueber M, O'Driscoll G, Jansz P, Khaghani A, Levy WC, Wieselthaler GM. Multicenter evaluation of an intrapericardial left ventricular assist system. J Am Coll Cardiol. 2011;57:1375–1382. - PubMed
-
- Starling RC, Naka Y, Boyle AJ, et al. Results of the Post-U.S. Food and Drug Administration-Approval Study With a Continuous Flow Left Ventricular Assist Device as a Bridge to Heart Transplantation A Prospective Study Using the INTERMACS (Interagency Registry for Mechanically Assisted Circulatory Support) J Am Coll Cardiol. 2011;57:1890–1898. - PubMed
-
- Romano MA, Cowger J, Aaronson KD, Pagani FD. Diagnosis and management of right-sided heart failure in subjects supported with left ventricular assist devices. Curr Treat Options Cardiovasc Med. 2010;12:420–430. - PubMed
-
- Moon MR, Castro LJ, DeAnda A, et al. Right ventricular dynamics during left ventricular assistance in closed-chest dogs. Ann Thorac Surg. 1993;56:54–66. discussion 66–7. - PubMed
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