Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2012 Mar 30;11(4):269-70.
doi: 10.1038/nrd3700.

Aflibercept

Michael W Stewart, Seden Grippon, Peter Kirkpatrick

Aflibercept

Michael W Stewart et al. Nat Rev Drug Discov. .

Abstract

In November 2011, aflibercept (Eylea; Regeneron Pharmaceuticals), a recombinant fusion protein that binds to members of the vascular endothelial growth factor family, was approved by the US Food and Drug Administration (FDA) for the treatment of patients with neovascular age-related macular degeneration.

PubMed Disclaimer

References

    1. Proc Natl Acad Sci U S A. 2002 Aug 20;99(17):11393-8 - PubMed
    1. Nat Rev Drug Discov. 2006 Oct;5(10):815-6 - PubMed
    1. N Engl J Med. 2011 May 19;364(20):1897-908 - PubMed
    1. Mayo Clin Proc. 2012 Jan;87(1):77-88 - PubMed

MeSH terms

Substances

LinkOut - more resources