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. 2010 Jan;7(1):61-4.

Pharmaco-economic issues in the treatment of severe osteoporosis

Prisco Piscitelli  1 , Giovanna Chitano, Marco Greco, Marco Benvenuto, Enzo Sbenaglia, Giuseppe Colì, Alberto Migliore, Mauro Granata, Giovanni Iolascon, Raffaele Gimigliano, Angelo Baggiani, Alessandro Distante, Umberto Tarantino, Carla Rizzuti, Maria Luisa Brandi
Affiliations

Pharmaco-economic issues in the treatment of severe osteoporosis

Prisco Piscitelli et al. Clin Cases Miner Bone Metab. 2010 Jan.

Abstract

Introduction: clinical guidelines recommend to identify and treat people at high risk of fracture.

Methods: we have carried out a simulation concerning pharmaco-economic issues in the treatment of severe osteoporosis and particularly those people with previous femoral fragility fractures, assuming that only 13.1% of hip fractured patients had started a proper antifracture therapy, as shown by the analysis of the Tuscany regional database.

Results: Annual costs sustained by the Italian healthcare system for treating hip fractured patients all over Italy have been estimated to range from 2 560 000 in year 2000 to 3 291 750 in year 2005, representing only 0,3% of the overall costs sustained because of hip fractures in Italy.

Conclusions: Sixty percent of the pharmacological costs can be considered as ineffective from a therapeutic point of view because patients were assuming their drugs only for 6 months. There is a need for specific codification of osteoporotic fragility fractures at hospital admissions and for implementing regional strategies aimed to reduce hip re-fractures by increasing the number of patients on treatment and incrementing adherence to treatment.

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