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Case Reports
. 2009 Oct;1(4):233-6.
doi: 10.4021/jocmr2009.09.1264. Epub 2009 Oct 16.

Malignant schwannoma of anterior abdominal wall: report of a case

Zhamak Khorgami  1 , Shirzad Nasiri, Freshteh Rezakhanlu, Nassim Sodagari
Affiliations
Case Reports

Malignant schwannoma of anterior abdominal wall: report of a case

Zhamak Khorgami et al. J Clin Med Res. 2009 Oct.

Abstract

Malignant schwannoma of the anterior abdominal wall nerves is extremely rare. Malignant peripheral nerve sheath tumors (MPNST) represent approximately 10% of all soft tissue sarcomas and it is found in 4% of patients with neurofibromatosis 1. We present a case of malignant schwannoma in a 28-year-old female patient with neurofibromatosis 1. She presented with a painful mass in the right upper quadrant of her abdomen. The tumor location was in the abdominal wall in explorative laparatomy and malignant schwannoma was diagnosed in pathologic assessment. The tumor recurred in 3 months and computed tomography showed two masses in the right side of abdominopelvic cavity. Thereafter, second complete surgical resection was performed and pathologic finding was the same. In spite of administering chemotherapy after second surgery,the tumor recurred and magnetic resonance imaging finding showed a huge heterogeneously enhancing mass with adhesion to the inner side of the abdominal wall. The patient died because of acute respiratory failure due to multiple bilateral pulmonary metastases. Tumor location and rapid recurrence was unique in our patient.

Keywords: Malignant peripheral nerve sheath tumor; Malignant schwannoma; Abdominal wall.

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Figures

Figure 1
Figure 1
Multiple cafe-au-lait spots scattered over the patient's entire body.
Figure 2
Figure 2
Abdominopelvic Computed Tumography shows a large mass in the right side of abdominal cavity.
Figure 3
Figure 3
Magnetic Resonance Imaging shows huge heterogeneously enhancing mass with some necrotic foci which has filled the abdominal and pelvic cavities.
See this image and copyright information in PMC

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