Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2012:2012:574656.
doi: 10.1155/2012/574656. Epub 2012 Feb 22.

Determinants of Adherence to Antiretroviral Therapy among HIV-Infected Patients in Africa

Affiliations

Determinants of Adherence to Antiretroviral Therapy among HIV-Infected Patients in Africa

Ayalu A Reda et al. AIDS Res Treat. 2012.

Abstract

Background. There are only a few comprehensive studies of adherence to ART and its challenges in Africa. This paper aims to assess the evidence on the challenges and prospects of ART adherence in sub-Saharan Africa. Methods. The authors reviewed original and review articles involving HIV-positive individuals that measured adherence to ART and its predictors in the past decade. Findings. Against expectations, sub-Saharan Africa patients have similar or higher adherence levels compared to those of developed countries. The challenges to ART adherence include factors related to patients and their families, socioeconomic factors, medication, and healthcare systems. Conclusion. Despite good adherence and program-related findings, antiretroviral treatment is challenged by a range of hierarchical and interrelated factors. There is substantial room for improvement of ART programs in sub-Sahara African countries.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Identified factors for the challenges of adherence to ART.

References

    1. United Nations Programme on HIV/AIDS. AIDS Epidemic Update. Geneva, Switzerland: United Nations Programme on HIV/AIDS (UNAIDS) and World Health Organization (WHO); 2009.
    1. Chi BH, Cantrell RA, Zulu I, et al. Adherence to first-line antiretroviral therapy affects non-virologic outcomes among patients on treatment for more than 12 months in Lusaka, Zambia. International Journal of Epidemiology. 2009;38(3):746–756. - PMC - PubMed
    1. Mills EJ, Bakanda C, Birungi J, et al. Life expectancy of persons receiving combination antiretroviral therapy in low-income countries: a cohort analysis from Uganda. Annals of Internal Medicine. 2011;155(4):209–217. - PubMed
    1. WHO. Towards universal access: scaling up priority HIV/AIDS interventions in the health sector: progress report 2010. In: WHO, editor. Geneva, Switzerland, WHO, 2010.
    1. Nachega JB, Mills EJ, Schechter M. Antiretroviral therapy adherence and retention in care in middle-income and low-income countries: current status of knowledge and research priorities. Current Opinion in HIV and AIDS. 2010;5(1):70–77. - PubMed

LinkOut - more resources