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. 2012 Apr;206(4):309.e1-7.
doi: 10.1016/j.ajog.2012.01.014.

The risk of stillbirth and infant death stratified by gestational age in women with gestational diabetes

Melissa G Rosenstein  1 , Yvonne W Cheng, Jonathan M Snowden, James M Nicholson, Amy E Doss, Aaron B Caughey
Affiliations

The risk of stillbirth and infant death stratified by gestational age in women with gestational diabetes

Melissa G Rosenstein et al. Am J Obstet Gynecol. 2012 Apr.

Abstract

Objective: We sought to compare the different mortality risks between delivery and expectant management in women with gestational diabetes mellitus (GDM).

Study design: This is a retrospective cohort study that included singleton pregnancies of women diagnosed with GDM delivering at 36-42 weeks' gestational age in California from 1997 through 2006. A composite mortality rate was developed to estimate the risk of expectant management at each gestational age incorporating the stillbirth risk during the week of continuing pregnancy plus the infant mortality risk at the gestational age 1 week hence.

Results: In women with GDM, the risk of expectant management is lower than the risk of delivery at 36 weeks (17.4 vs 19.3/10,000), but at 39 weeks, the risk of expectant management exceeds that of delivery (relative risk, 1.8; 95% confidence interval, 1.2-2.6).

Conclusion: In women with GDM, infant mortality rates at 39 weeks are lower than the overall mortality risk of expectant management for 1 week; absolute risks of stillbirth and infant death are low.

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Conflict of interest statement

Disclosure: None of the authors have a conflict of interest.

Figures

Figure 1
Figure 1. Infant Death and Stillbirth Rates in Women With and Without Gestational Diabetes Mellitus (GDM)
This figure graphically compares the gestational-age specific rates of stillbirth and infant death in women with and without gestational diabetes mellitus (GDM).
Figure 2
Figure 2. The Mortality Risk of Expectant Management Compared with Delivery in Women with Gestational Diabetes Mellitus (GDM)
This figure compares the risk of expectant management for one week (calculated as the risk of stillbirth this week plus the risk of infant death at the subsequent week) compared with the risk of delivery (calculated as the risk of infant death at that gestational week) at each gestational age week from 36-41 weeks.
See this image and copyright information in PMC

References

    1. Maternal, Child, and Adolescent Health Program/Epidemiology, Assessment and Program Developement. Gestational diabetes mellitus. Sacramento, CA: California Department of Publis; 2008.
    1. Mitanchez D. Foetal and neonatal complications in gestational diabetes: Perinatal mortality, congenital malformations, macrosomia, shoulder dystocia, birth injuries, neonatal complications. Diabetes Metab. 2010 Dec;36(6 Pt 2):617–27. - PubMed
    1. American College of Obstetricians and Gynecologists Committee on Practice Bulletins--Obstetrics. ACOG Practice Bulletin. Clinical management guidelines for obstetrician-gynecologists. Number 30, September 2001 (replaces Technical Bulletin Number 200, December 1994). Gestational Diabetes. Obstet Gynecol. 2001 Sep;98(3):525–38. - PubMed
    1. O’Sullivan JB, Gellis SS, Dandrow RV, Tenney BO. The potential diabetic and her treatment in pregnancy. Obstet Gynecol. 1966 May;27(5):683–9.
    1. Pettitt DJ, Knowler WC, Baird HR, Bennett PH. Gestational diabetes: Infant and maternal complications of pregnancy in relation to third-trimester glucose tolerance in the Pima Indians. Diabetes Care. 1980 May-Jun;3(3):458–64. - PubMed

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