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Review
. 2012 Mar 30;17(4):3866-89.
doi: 10.3390/molecules17043866.

Chemistry and biological activities of terpenoids from copaiba (Copaifera spp.) oleoresins

Lidiam Maia Leandro  1 , Fabiano de Sousa Vargas, Paula Cristina Souza Barbosa, Jamilly Kelly Oliveira Neves, José Alexsandro da Silva, Valdir Florêncio da Veiga-Junior
Affiliations
Review

Chemistry and biological activities of terpenoids from copaiba (Copaifera spp.) oleoresins

Lidiam Maia Leandro et al. Molecules. .

Abstract

Copaiba oleoresins are exuded from the trunks of trees of the Copaifera species (Leguminosae-Caesalpinoideae). This oleoresin is a solution of diterpenoids, especially, mono- and di-acids, solubilized by sesquiterpene hydrocarbons. The sesquiterpenes and diterpenes (labdane, clerodane and kaurane skeletons) are different for each Copaifera species and have been linked to several reported biological activities, ranging from anti-tumoral to embriotoxic effects. This review presents all the substances already described in this oleoresin, together with structures and activities of its main terpenoids.

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Figures

Figure 1
Figure 1
Main sesquiterpenes detected in copaiba oleoresin.
Figure 2
Figure 2
Main diterpenes detected in copaiba oleoresin.
See this image and copyright information in PMC

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