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Case Reports
. 2011 Jan;1(1):69-72.
doi: 10.1159/000331217. Epub 2011 Sep 8.

Crescentic glomerulonephritis in IgA multiple myeloma: a case report

Grace T Moscoso-Solorzano  1 , Marcus V Madureira-Silva, Carlos Balda, Marcello F Franco, Gianna Mastroianni-Kirsztajn
Affiliations
Case Reports

Crescentic glomerulonephritis in IgA multiple myeloma: a case report

Grace T Moscoso-Solorzano et al. Nephron Extra. 2011 Jan.

Abstract

Background: There are few reports of glomerulonephritis (GN) with crescents and a rapidly progressive course that lead to a diagnosis of a previously unsuspected B-cell dyscrasia.

Case presentation: We report a case of rapidly progressive GN: the patient showed no evidence of etiology at the time of biopsy and was diagnosed as IgA multiple myeloma (MM) during investigation based on a renal biopsy. He presented diffuse proliferative and exudative GN and marked plasma cell infiltration of the kidney.

Conclusion: The present case raises the possibility that proliferative GN with crescents may be a rare mode of presentation of MM.

Keywords: B-cell dyscrasia; Crescents; Glomerulonephritis; Multiple myeloma; Rapidly progressive glomerulonephritis.

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Figures

Fig. 1
Fig. 1
Proliferative and exudative acute GN. HE. ×200.
Fig. 2
Fig. 2
Foci of neoplastic infiltration of plasma cells (MM).
See this image and copyright information in PMC

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