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. 2010;4(8):29-35.
doi: 10.3941/jrcr.v4i8.474. Epub 2010 Aug 1.

Endobronchial granular cell tumor: a case report

Monique Anne Meyer  1 , Joseph M Becker, William Quinones
Affiliations

Endobronchial granular cell tumor: a case report

Monique Anne Meyer et al. J Radiol Case Rep. 2010.

Abstract

Granular cell tumors (GCTs) are benign neoplasms that are most commonly found in the head and neck region. We present a case of endobronchial granular cell tumor presenting as hemoptysis in a 22-year-old African American female. Patient subsequently underwent a right upper and middle lobectomy, and upon histologic analysis was found to have GCT with borders impinging upon cartilage and adjacent peribronchial lymph nodes.

Keywords: Granular cell tumor; endobronchial.

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Figures

Figure 1
Figure 1
22-year-old female diagnosed with endobronchial granular cell tumor. PA and lateral chest radiographs, arrow points to a rounded right hilar prominence and volume loss in the right upper lobe with associated patchy right upper lobe density.
Figure 2
Figure 2
22-year-old female diagnosed with endobronchial granular cell tumor. Axial (left image) and coronal (right image) contrast-enhanced CT images of the chest (GE brand scanner, 40 mA, 120 kV, obtained at 2.5 mm slice thickness, after adminatration of 90 mL of Optiview iodintated intravenous contrast). Arrow points to a soft tissue mass in the right hilar region measuring approximately 30 × 29 × 27 mm. The soft tissue encases and narrows the right upper lobe bronchus with incomplete atelectasis of this lobe and with bronchiectatic changes in its the posterior segment.
Figure 3
Figure 3
22-year-old female diagnosed with endobronchial granular cell tumor. Granular cell tumor (10× magnification) stained with periodic acid-schiff. Large polygonal cells with highly granular eosinophilic cytoplasm and central, small, dark, uniform nuclei.
Figure 4
Figure 4
22-year-old female diagnosed with endobronchial granular cell tumor. Granular cell tumor (40× magnification) stained with periodic acid-schiff. The cytoplasm contains innumerable fine cytoplasmic granules as well as scattered large eosinophilic globules.
Figure 5
Figure 5
22-year-old female diagnosed with endobronchial granular cell tumor. Granular cell tumor (40× magnification) stained with periodic acid-schiff infiltrating up to the bronchial cartilage.
Figure 6
Figure 6
22-year-old female diagnosed with endobronchial granular cell tumor. Granular cell tumor (40× magnification) stained with periodic acid-schiff compressing on pulmonary interstitial lymphoid tissue.
See this image and copyright information in PMC

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