Cohesin in determining chromosome architecture
- PMID: 22472347
- DOI: 10.1016/j.yexcr.2012.03.016
Cohesin in determining chromosome architecture
Abstract
Cells use ring-like structured protein complexes for various tasks in DNA dynamics. The tripartite cohesin ring is particularly suited to determine chromosome architecture, for it is large and dynamic, may acquire different forms, and is involved in several distinct nuclear processes. This review focuses on cohesin's role in structuring chromosomes during mitotic and meiotic cell divisions and during interphase.
Copyright © 2012 Elsevier Inc. All rights reserved.
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