A novel anticancer diterpenoid from Jatropha gossypifolia
Affiliations
- PMID: 22474940
Item in Clipboard
A novel anticancer diterpenoid from Jatropha gossypifolia
Nat Prod Commun.
2012 Feb.
Abstract
Jatropha gossypifolia root bark is used in ethnomedicine for bacterial infections and cancer of the lungs. Phytochemical investigation resulted in the isolation and characterization of a potent anticancer and novel lathyrane diterpenoid compound, abiodone, with an unusual methylene group. The structure of this novel compound was established by 1D, and 2D NMR spectroscopic experiments a nd confirmed by X-ray analysis.
Similar articles
-
Spirocurcasone, a diterpenoid with a novel carbon skeleton from Jatropha curcas.Org Lett. 2011 Jan 21;13(2):316-9. doi: 10.1021/ol102802u. Epub 2010 Dec 9. Org Lett. 2011. PMID: 21141918
-
Multifidone: a novel cytotoxic lathyrane-type diterpene having an unusual six-membered A ring from Jatropha multifida.Bioorg Med Chem Lett. 2009 Jan 1;19(1):77-9. doi: 10.1016/j.bmcl.2008.11.014. Epub 2008 Nov 9. Bioorg Med Chem Lett. 2009. PMID: 19036584
-
New bioactive macrocyclic diterpenoids from Jatropha multifida.Bioorg Med Chem Lett. 2011 Nov 15;21(22):6808-10. doi: 10.1016/j.bmcl.2011.09.032. Epub 2011 Sep 22. Bioorg Med Chem Lett. 2011. PMID: 21996519
-
Japodagricanones A and B, novel diterpenoids from Jatropha podagrica.Fitoterapia. 2014 Oct;98:156-9. doi: 10.1016/j.fitote.2014.07.021. Epub 2014 Aug 1. Fitoterapia. 2014. PMID: 25088971
-
A review on pharmacological significance of genus Jatropha (Euphorbiaceae).Chin J Integr Med. 2012 Nov;18(11):868-80. doi: 10.1007/s11655-012-1267-8. Epub 2012 Oct 20. Chin J Integr Med. 2012. PMID: 23086490 Review.
Cited by
-
Jatropha gossypiifolia L. (Euphorbiaceae): A Review of Traditional Uses, Phytochemistry, Pharmacology, and Toxicology of This Medicinal Plant.Evid Based Complement Alternat Med. 2014;2014:369204. doi: 10.1155/2014/369204. Epub 2014 Jun 5. Evid Based Complement Alternat Med. 2014. PMID: 25002902 Free PMC article. Review.
-
Isolation of antileishmanial, antimalarial and antimicrobial metabolites from Jatropha multifida.Asian Pac J Trop Biomed. 2014 May;4(5):374-8. doi: 10.12980/APJTB.4.2014C1312. Asian Pac J Trop Biomed. 2014. PMID: 25182722 Free PMC article.