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. 1979 Jun;15(6):813-9.
doi: 10.1128/AAC.15.6.813.

Preliminary studies of the mode of action of arildone, a novel antiviral agent

M F Kuhrt, M J Fancher, V Jasty, F Pancic, P E Came

Preliminary studies of the mode of action of arildone, a novel antiviral agent

M F Kuhrt et al. Antimicrob Agents Chemother. 1979 Jun.

Abstract

Arildone (also known as Win 38020), a novel aryl diketone, inhibited replication of herpes simplex virus type 2 in tissue culture by interfering with an event that occurs prior to 6 h postinfection. The inhibition could be partially reversed by washing. Although the exact mechanism of action is unknown, neither viral deoxyribonucleic acid nor viral proteins were synthesized in the presence of arildone.

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References

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