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Review
. 2012 Apr 4;15(4):432-7.
doi: 10.1016/j.cmet.2011.11.013.

Orchestration of metabolism by macrophages

Subhra K Biswas  1 , Alberto Mantovani
Affiliations
Free article
Review

Orchestration of metabolism by macrophages

Subhra K Biswas et al. Cell Metab. .
Free article

Abstract

Metabolic adaptation is a key component of macrophage plasticity and polarization, instrumental to their function in homeostasis, immunity, and inflammation. Macrophage products also impact metabolism, as illustrated by obesity-associated pathologies. Defining the mechanisms regulating macrophage metabolic activity and orchestration of metabolism by macrophages is crucial to pathology and therapeutic intervention.

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