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. 2012 Apr 3:344:e2161.
doi: 10.1136/bmj.e2161.

Personalised medicine: not just in our genes

Georgios D Kitsios  1 , David M Kent
Affiliations

Personalised medicine: not just in our genes

Georgios D Kitsios et al. BMJ. .

Abstract

Despite the identification of numerous gene-drug associations, few have been incorporated into clinical practice or guidelines. Georgios D Kitsios and David M Kent argue that if personalised medicine is to become a reality we have to look beyond our genes

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Conflict of interest statement

Completing interests: All authors have completed the ICMJE uniform disclosure form at www.icmje.org/coi_disclosure.pdf (available on request from the corresponding author) and declare partial funding of the work in this article from the National Institute of Health (UL1RR025752); no financial relationships with any organisations that might have an interest in the submitted work in the previous three years; and no other relationships or activities that could appear to have influenced the submitted work.

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References

    1. Hindorff LA, Sethupathy P, Junkins HA, Ramos EM, Mehta JP, Collins FS, et al. Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci USA 2009;106:9362-7. - PMC - PubMed
    1. Janssens AC, van Duijn CM. An epidemiological perspective on the future of direct-to-consumer personal genome testing. Invest Genet 2010;1:10. - PMC - PubMed
    1. Goldstein DB. Common genetic variation and human traits. N Engl J Med 2009;360:1696-8. - PubMed
    1. Ioannidis JP. Prediction of cardiovascular disease outcomes and established cardiovascular risk factors by genome-wide association markers. Circ Cardiovasc Genet 2009;2:7-15. - PubMed
    1. Manolio TA, Collins FS, Cox NJ, Goldstein DB, Hindorff LA, Hunter DJ, et al. Finding the missing heritability of complex diseases. Nature 2009;461:747-53. - PMC - PubMed

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