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. 2012 Jun;50(6):2069-71.
doi: 10.1128/JCM.00745-12. Epub 2012 Apr 4.

Multiplex PCR for rapid and improved diagnosis of bloodstream infections in liver transplant recipients

Peter-Michael Rath  1 , Fuat Saner, Andreas Paul, Nils Lehmann, Eike Steinmann, Jan Buer, Joerg Steinmann
Affiliations

Multiplex PCR for rapid and improved diagnosis of bloodstream infections in liver transplant recipients

Peter-Michael Rath et al. J Clin Microbiol. 2012 Jun.

Abstract

This prospective study evaluated the utility of the SeptiFast (SF) test in detecting 25 clinically important pathogens in 225 blood samples from 170 intensive care unit (ICU) patients with suspected sepsis after liver transplantation (LTX) or after other major abdominal surgery (non-LTX). SF yielded a significantly higher positivity rate in the LTX group (52.3%) than in the non-LTX group (30.5%; P = 0.0009). SF may be a powerful tool for the early diagnosis of bloodstream infections in LTX patients.

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