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. 1979 Sep 3;586(3):608-14.
doi: 10.1016/0304-4165(79)90051-5.

Inhibition of the degradation of receptor-bound human choriogonadotropin by leupeptin

Inhibition of the degradation of receptor-bound human choriogonadotropin by leupeptin

M Ascoli. Biochim Biophys Acta. .

Abstract

The ability of leupeptin to block the degradation of receptor-bound human choriogonadotropin has been studied. It was found that this compound inhibited hormone degradation and intracellular cathepsin B activity in a parallel fasion, without affecting hormone-stimulated steroidogenesis.

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