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Case Reports
. 2012 Jun;50(6):2173-5.
doi: 10.1128/JCM.00573-12. Epub 2012 Apr 11.

Fatal case of brucellosis misdiagnosed in early stages of Brucella suis infection in a 46-year-old patient with Marfan syndrome

M Carrington  1 , U Choe, S Ubillos, D Stanek, M Campbell, L Wansbrough, P Lee, G Churchwell, K Rosas, S R Zaki, C Drew, C D Paddock, M Deleon-Carnes, M Guerra, A R Hoffmaster, R V Tiller, B K De
Affiliations
Case Reports

Fatal case of brucellosis misdiagnosed in early stages of Brucella suis infection in a 46-year-old patient with Marfan syndrome

M Carrington et al. J Clin Microbiol. 2012 Jun.

Abstract

We report a fatal case of Brucella suis endocarditis initially misdiagnosed by automated identification systems as Ochrobactrum anthropi infection in a patient with a history of Marfan syndrome and recreational feral swine hunting. This report emphasizes the need to consider brucellosis as a part of the differential diagnosis of acute febrile illness, particularly in patients with known risk of exposure.

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References

    1. Animal and Plant Health Inspection Service 2005. Feral/wild pigs: potential problems for farmers and hunters. U.S. Department of Agriculture agriculture information bulletin no. 799. U.S. Department of Agriculture, Washington, DC
    1. Barquero-Calvo E, et al. 2009. The differential interaction of Brucella and Ochrobactrum with innate immunity reveals traits related to the evolution of stealthy pathogens. PLoS One 4:e5893 doi: - DOI - PMC - PubMed
    1. Carrington M, et al. 2011. A fatal case of brucellosis in early stages of B. suis infection in a 46-year-old patient with Marfan syndrome, poster P60, p 84 Abstr. Brucellosis 2011 Int. Res. Conf. Asociacion Argentina de Microbiologia, Buenos Aires, Argentina
    1. CDC 2009. Brucella suis infection associated with feral swine hunting—three states, 2007-2008. MMWR Morb. Mortal. Wkly. Rep. 58:618–621 - PubMed
    1. CDC 2008. Laboratory-acquired brucellosis—Indiana and Minnesota, 2006. MMWR Morb. Mortal. Wkly. Rep. 57:39–42 - PubMed

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