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. 2012 May 14;10(18):3763-6.
doi: 10.1039/c2ob25512j. Epub 2012 Apr 3.

Gold(I)-catalyzed intramolecular hydroamination and ring-opening of sulfonamide-substituted 2-(arylmethylene)cyclopropylcarbinols

Di-Han Zhang  1 , Kang Du, Min Shi
Affiliations

Gold(I)-catalyzed intramolecular hydroamination and ring-opening of sulfonamide-substituted 2-(arylmethylene)cyclopropylcarbinols

Di-Han Zhang et al. Org Biomol Chem. .

Abstract

An interesting gold(I)-catalyzed intramolecular hydroamination and ring-opening of sulfonamide-substituted 2-(arylmethylene)cyclopropylcarbinols has been described in this context. A variety of 4-substituted isoxazolidine derivatives were obtained in good to high yields through a highly regioselective cleavage of a carbon-carbon single bond in the cyclopropane.

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