Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2012;8(4):e1002585.
doi: 10.1371/journal.ppat.1002585. Epub 2012 Apr 5.

Fungal biofilms

Saranna Fanning  1 , Aaron P Mitchell
Affiliations

Fungal biofilms

Saranna Fanning et al. PLoS Pathog. 2012.
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Common features of fungal biofilms.
Gene expression has been compared between planktonic cells and biofilm cells of both A. fumigatus and C. albicans. The major functional categories of genes upregulated in biofilms are summarized in the blue box. The micrographs below show a cryo SEM view of an A. fumigatus biofilm (left; Stephanie Guadagnini, Anne Beauvais, and J.P. Latge, Institut Pasteur, Paris, France) and a scanning EM view of C. albicans in vitro biofilm cells (right; Fanning, Suhan, and Mitchell, unpublished). In both cases, extracellular matrix (ECM) is evident.
See this image and copyright information in PMC

References

    1. Finkel JS, Mitchell AP. Genetic control of Candida albicans biofilm development. Nat Rev Microbiol. 2011;9:109–118. - PMC - PubMed
    1. Beauvais A, Muller FM. Biofilm formation in Aspergillus fumigatus. In: Latge JP, Steinbach WJ, editors. Aspergillus fumigatus and aspergillosis. Washington (D.C.): ASM Press; 2009. pp. 149–157.
    1. Martinez LR, Casadevall A. Cryptococcus neoformans biofilm formation depends on surface support and carbon source and reduces fungal cell susceptibility to heat, cold, and UV light. Appl Environ Microbiol. 2007;73:4592–4601. - PMC - PubMed
    1. Di Bonaventura G, Pompilio A, Picciani C, Iezzi M, D'Antonio D, et al. Biofilm formation by the emerging fungal pathogen Trichosporon asahii: development, architecture, and antifungal resistance. Antimicrob Agents Chemother. 2006;50:3269–3276. - PMC - PubMed
    1. Davis LE, Cook G, Costerton JW. Biofilm on ventriculo-peritoneal shunt tubing as a cause of treatment failure in coccidioidal meningitis. Emerg Infect Dis. 2002;8:376–379. - PMC - PubMed

Publication types

MeSH terms

Substances