Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1990 Oct;14(5):561-9.
doi: 10.1007/BF00914276.

Characterization of leukocyte chemotactic activity of bacteriocin from Streptococcus mutans Rm-10

Y Tsukamoto  1 , S Fukutani, Y Takayama, H Fukushima, H Sagawa, M Mori
Affiliations

Characterization of leukocyte chemotactic activity of bacteriocin from Streptococcus mutans Rm-10

Y Tsukamoto et al. Inflammation. 1990 Oct.

Abstract

Bacteriocins have several biological activities in addition to their antibacterial effect. We investigated the chemotactic properties and mode of action of purified streptococcal bacteriocin. Bacteriocin purified from a culture supernatant of Streptococcus mutans (S. mutans) Rm-10 induced chemotaxis of human polymorphonuclear leukocytes and monocytes. Following purification, leukocyte migration appeared in one bacteriocin fraction, and this migration was dependent on the concentration gradient in dilution ranges from 1/960 to 1/15. Chemotactic activity of the bacteriocin was heat labile and trypsin sensitive. Moreover, preincubation of bacteriocin with varying dilutions of its antiserum prepared in rabbits resulted in a significant loss of the chemotactic activity.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. J Immunol. 1975 Jun;114(6):1831-7 - PubMed
    1. J Immunol. 1975 Dec;115(6):1650-6 - PubMed
    1. Arch Oral Biol. 1982;27(9):721-7 - PubMed
    1. J Immunol Methods. 1980;33(3):239-47 - PubMed
    1. Clin Immunol Immunopathol. 1975 Jan;3(3):334-46 - PubMed

MeSH terms