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Comment
. 2012 Apr 13;149(2):257-9.
doi: 10.1016/j.cell.2012.03.020.

Sgs1--the maestro of recombination

Hannah L Klein  1 , Lorraine S Symington
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Free article
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Sgs1--the maestro of recombination

Hannah L Klein et al. Cell. .
Free article

Abstract

The Sgs1 DNA helicase and its mammalian homolog BLM control crossover formation in mitotic cells. Zakharyevich et al. and De Muyt et al. now uncover a key role for Sgs1 in meiotic crossover regulation, which in turn reveals a joint molecule resolution pathway that produces the majority of crossovers in budding yeast.

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