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Case Reports
. 1990 Aug;32(8):923-8.

Exercise-induced acute renal failure in 3 patients with renal hypouricemia

I Ishikawa  1 , Y Sakurai, S Masuzaki, N Sugishita, A Shinoda, N Shikura
Affiliations
  • PMID: 2250410
Case Reports

Exercise-induced acute renal failure in 3 patients with renal hypouricemia

I Ishikawa et al. Nihon Jinzo Gakkai Shi. 1990 Aug.

Abstract

Three cases of exercise-induced non-oliguric acute renal failure in patients with renal hypouricemia, an isolated defect of the renal urate transport system, are described. During acute renal failure, the serum uric acid levels were 5.6, 2.7 and 5.8 mg/dl, respectively, and were within normal limits. The values representing the fractional excretion of uric acid (FEUA) were 28.7, 60.0 and 12.7%, with accompanying serum creatinine levels of 8.1, 3.9 and 3.3 mg/dl, respectively. After recovery, the serum uric acid fell to 0.6, 0.7 and 1.0 mg/dl and the FEUA increased to 79.3, 52.8 and 43.2%, respectively. Two of the patients examined exhibited decreased reabsorption of filtered urate. These 3 examples of renal hypouricemia represented 23% of 13 cases of mild exercise-induced acute renal failure encountered within our experience.

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