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. 2009 Apr;1(1):40-4.
doi: 10.4021/jocmr2009.03.1226. Epub 2009 Mar 24.

Carotid atherosclerosis in ischemic cerebrovascular patients

Ai Juan Zhang  1 , Ai Yuan Zhang, Chi Zhong
Affiliations

Carotid atherosclerosis in ischemic cerebrovascular patients

Ai Juan Zhang et al. J Clin Med Res. 2009 Apr.

Abstract

Background: Cerebral emboli resulting from atherosclerosis at the carotid bifurcation is a major cause of ischemic stroke. A convenient and prompt evaluation is necessary for secondary prevention and treatment.

Methods: In this study, one hundred and thirty eight patients with cerebral ischemic events were enrolled; 100 patients with nonischemic cerebral diseases were enrolled as controls. Noninvasive ultrasound was used to measure the atherosclerotic plaques and intima-media thickness (IMT) of carotid and femoral artery.

Results: Our results showed that patients in study group had higher incidence and severity of carotid and femoral plaques, and higher mean intima-media thickness (IMT) at both the carotid and femoral sites compared with that of controls (p < 0.01). Carotid atherosclerosis were highly prone to have instability plaques in study group(p < 0.001).

Conclusions: This cross-sectional study showed that, the prevalence of carotid atherosclerosis and the unstable plaques were higher in cerebral ischemic patients.

Keywords: Carotid artery; Atherosclerosis; Intima-media thickness; Cerebral ischemic stroke.

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Figures

Figure 1
Figure 1
Mean Ridit values in study and control groups, p < 0.01.
See this image and copyright information in PMC

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