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Review
. 2012 Jun;55(2):521-30.
doi: 10.1097/GRF.0b013e3182510b7b.

Prevention of maternal and congenital cytomegalovirus infection

Julie Johnson  1 , Brenna Anderson, Robert F Pass
Affiliations
Review

Prevention of maternal and congenital cytomegalovirus infection

Julie Johnson et al. Clin Obstet Gynecol. 2012 Jun.

Abstract

Congenital cytomegalovirus (CMV) infection is an important cause of hearing impairment, mental retardation, and cerebral palsy. Principal sources of infection during pregnancy are young children and intimate contacts. Prevention of maternal and congenital CMV infection depends on counseling women regarding the sources of infection and hygienic measures that might prevent infection. There is currently insufficient evidence to support use of antiviral treatment or passive immunization for postexposure prophylaxis of pregnant women or as a maternal treatment aimed at preventing fetal infection. Vaccines for CMV are under development but it will be a number of years before one is licensed.

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Conflict of interest statement

Conflicts of Interest and Source of Funding: JJ has nothing to declare. BA receives research funding from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) K23 HD062340-01 and has no conflicts to declare. RFP has received funding from the National Institutes of Allergy, Immunology and Infectious Diseases (U01-AI063565) and from Sanofi Pasteur and is a consultant to Astellas, Merck and the State of Montana Attorney General’s office.

References

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