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. 2012 Apr 18;10(1):4.
doi: 10.1186/1477-9560-10-4.

Cold autoimmune haemolytic anaemia secondary to Epstein Barr virus infection presenting with peripheral gangrene; case report

Suneth Karunarathne  1 , Sajitha Weerasinghe, Dumitha Govindapala, Harshini Fernando, Bhaddika Jayaratne
Affiliations

Cold autoimmune haemolytic anaemia secondary to Epstein Barr virus infection presenting with peripheral gangrene; case report

Suneth Karunarathne et al. Thromb J. .

Abstract

A sixty year old male presented with dark urine, symptomatic anaemia and peripheral gangrene following cold exposure. Investigations revealed that he had haemolysis and serological evidence of recent Epstein Barr virus infection. Although acrocyanosis is commonly associated with cold agglutinin disease, gangrene is a rare complication. Management of secondary cold agglutinin disease is mainly supportive.

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Figures

Figure 1
Figure 1
Dry gangrene of fingertips involving nine out of the ten fingers.
Figure 2
Figure 2
Dry gangrene of toes and forefoot with clear demarcation.
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