Seroprevalence of toxoplasma antibody in a Toronto population
- PMID: 22514458
- PMCID: PMC3327420
- DOI: 10.1155/1996/172651
Seroprevalence of toxoplasma antibody in a Toronto population
Abstract
Objective: To determine the prevalence of infection with toxoplasmosis by country of birth and age in a sample of convenience.
Design: Banked sera and the computerized data base of demographic and other factors from an earlier epidemiological study were retrieved.
Setting: Thirty-eight infant-toddler day care centres in Toronto.
Population: Day care providers from whom informed consent was obtained and banked sera were available.
Main results: Of the 124 providers whose serum was tested, 16 (12.9%) were seropositive. Of those providers born in Canada, 8.2% were seropositive, while of those born outside of Canada, 19.6% were positive (P=0.067, OR 2.68, 95% CI 0.91, 7.94). While there was no significant association of seropositivity with age, the association of seropositivity with country of birth was different in the providers under 30 years of age. Among those born in Canada, 4.6% were seropositive, while among those born outside of Canada 23.1% were seropositive.
Conclusions: The data supplement the limited existing data on toxoplasmosis infection in Canada. Among Canadians, those born outside of Canada were more likely to be seropositive than those born in Canada, suggesting that there may be a differential risk of congenital infection for infants whose parents were born outside of Canada.
OBJECTIF :: Déterminer la prévalence de la toxoplasmose selon le pays d’origine et selon l’âge dans un échantillon de commodité.
MODÈLE :: Sérum mis en réserve et base de données informatisée des facteurs démographiques et autres, à partir d’une étude épidémiologique antérieure.
CONTEXTE :: Trente-huit garderies de Toronto.
POPULATION :: Préposés aux garderies de qui un consentement éclairé a été obtenu et chez qui on a prélevé des échantillons sériques mis en réserve.
PRINCIPAUX RÉSULTATS :: Parmi les 124 moniteurs dont le sérum avait été prélevé, 16 (12,9 %) étaient séropositifs. Parmi ceux d’origine canadienne, 8,2 % étaient positifs, alors que chez ceux qui étaient nés à l’extérieur du Canada, 19,6 % étaient positifs (P = 0,067, RR 2,68, IC 95 % 0,91, 7,94). Si aucune association significative de séropositivité n’a pu être établie avec l’âge, l’association de la séropositivité avec le pays d’origine a été différente chez les moniteurs de moins de 30 ans. Parmi les moniteurs nés au Canada, 4,6 % étaient séropositifs, alors que parmi ceux qui étaient nés à l’extérieur du Canada, 23,1 % l’étaient.
CONCLUSIONS :: Les données complètent les résultats limités existants sur la toxoplasmose au Canada. Parmi les Canadiens, les gens d’une autre origine étaient plus susceptibles d’être séropositifs que les Canadiens d’origine, ce qui donne à penser qu’il pourrait y avoir un risque différentiel d’infection congénitale pour les nourrissons dont les parents sont nés à l’extérieur du Canada.
Keywords: Day care; Seroprevalence; Toxoplasmosis.
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