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. 2012 May;18(5):834-7.
doi: 10.3201/eid1805.111922.

Human infections with novel reassortant influenza A(H3N2)v viruses, United States, 2011

Affiliations

Human infections with novel reassortant influenza A(H3N2)v viruses, United States, 2011

Stephen Lindstrom et al. Emerg Infect Dis. 2012 May.

Abstract

During July-December 2011, a variant virus, influenza A(H3N2)v, caused 12 human cases of influenza. The virus contained genes originating from swine, avian, and human viruses, including the M gene from influenza A(H1N1)pdm09 virus. Influenza A(H3N2)v viruses were antigenically distinct from seasonal influenza viruses and similar to proposed vaccine virus A/Minnesota/11/2010.

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Figures

Figure 1
Figure 1
Derivation of genes segments of novel influenza A(H3N2) viruses isolated from humans, United States, 1990–2011. TR-SIV, triple reassortant swine influenza virus.
Figure 2
Figure 2
Phylogenetic analysis of the A) hemagglutinin and B) matrix genes of influenza A(H3N2)v viruses. Sequences obtained from human A(H3N2)v isolates in the United States during 2011 are shown in boldface; sequences of proposed vaccine virus are underlined. Scale bars indicate number of base substitutions per site.

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