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Case Reports
. 2012 Jul;50(7):2489-91.
doi: 10.1128/JCM.06710-11. Epub 2012 Apr 18.

OXA-163-producing Klebsiella pneumoniae in Cairo, Egypt, in 2009 and 2010

Mohammed O Abdelaziz  1 , Celestino Bonura, Aurora Aleo, Ramadan A El-Domany, Teresa Fasciana, Caterina Mammina
Affiliations
Case Reports

OXA-163-producing Klebsiella pneumoniae in Cairo, Egypt, in 2009 and 2010

Mohammed O Abdelaziz et al. J Clin Microbiol. 2012 Jul.

Abstract

Two genetically unrelated OXA-163-carrying Klebsiella pneumoniae strains were identified from two infection cases in June 2009 and May 2010 in Cairo, Egypt. OXA-163-producing Enterobacteriaceae had been previously reported in Argentina only. Both patients had no history of travel abroad. The emergence of this newly recognized OXA-48-related β-lactamase able to hydrolyze cephalosporins and carbapenems is especially worrying in a geographic area where OXA-48 is endemic and effective surveillance for antibiotic resistance is largely unaffordable.

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Figures

Fig 1
Fig 1
XbaI pulsed-field gel electrophoresis patterns and rep-PCR patterns of two OXA-163-carrying Klebsiella pneumoniae strains, Cairo, Egypt, 2009 and 2010. (A) Lanes: MW, XbaI-digested DNA of Salmonella Braenderup H9812; 1, K. pneumoniae strain 18; 2, K. pneumoniae strain 78. (B) Lanes: 1, K. pneumoniae strain 18; 2, K. pneumoniae strain 78.
See this image and copyright information in PMC

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