M(odu)LLating the innate response
- PMID: 22520848
- DOI: 10.1016/j.immuni.2012.04.002
M(odu)LLating the innate response
Abstract
The integration of chromatin modifiers into specific regulatory networks is not fully understood. In this issue of Immunity, Austenaa et al. (2012) demonstrate a specific role for the histone methyltransferase MLL4 (Wbp7) in controlling the expression of critical molecules in the Toll-like receptor pathway.
Copyright © 2012 Elsevier Inc. All rights reserved.
Comment on
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The histone methyltransferase Wbp7 controls macrophage function through GPI glycolipid anchor synthesis.Immunity. 2012 Apr 20;36(4):572-85. doi: 10.1016/j.immuni.2012.02.016. Epub 2012 Apr 5. Immunity. 2012. PMID: 22483804
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