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Comment
. 2012 Apr 20;36(4):553-5.
doi: 10.1016/j.immuni.2012.04.003.

STATus report on tetramers

David E Levy  1 , Isabelle J Marié
Affiliations
Free article
Comment

STATus report on tetramers

David E Levy et al. Immunity. .
Free article

Abstract

STAT proteins bind DNA as dimers to regulate gene expression. Cooperative recruitment of pairs of dimers (tetramers) to adjacent DNA sites has also been documented. In this issue, Lin et al. (2012) examined tetramer function in vivo and showed that STAT5 tetramers function primarily as transcriptional activators.

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