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Clinical Trial
. 2013 Jan;7(1):11-3.
doi: 10.1111/j.1750-2659.2012.00367.x. Epub 2012 Apr 23.

Safety and tolerability of a 6-week course of oseltamivir prophylaxis for seasonal influenza in children

Keith Reisinger  1 , Daniel Shu, Lisa Cupelli, Isaac Marcadis, Regina Dutkowski
Affiliations
Clinical Trial

Safety and tolerability of a 6-week course of oseltamivir prophylaxis for seasonal influenza in children

Keith Reisinger et al. Influenza Other Respir Viruses. 2013 Jan.

Abstract

In an open-label study, 49 children aged 1-12 years received oseltamivir (30-75 mg once daily depending on bodyweight) for 6 weeks for influenza prophylaxis. Seventeen participants reported 22 adverse events (AEs); in three participants, AEs were considered probably drug related (nausea or vomiting). No serious AEs were reported. The tolerability profile was similar to pooled safety data from treatment studies (duration of 5 days) in children.

Trial registration: ClinicalTrials.gov NCT00412555.

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