Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2012 Jun;19(e1):e36-42.
doi: 10.1136/amiajnl-2012-000968. Epub 2012 Apr 20.

Clinical research informatics: a conceptual perspective

Michael G Kahn  1 , Chunhua Weng
Affiliations

Clinical research informatics: a conceptual perspective

Michael G Kahn et al. J Am Med Inform Assoc. 2012 Jun.

Abstract

Clinical research informatics is the rapidly evolving sub-discipline within biomedical informatics that focuses on developing new informatics theories, tools, and solutions to accelerate the full translational continuum: basic research to clinical trials (T1), clinical trials to academic health center practice (T2), diffusion and implementation to community practice (T3), and 'real world' outcomes (T4). We present a conceptual model based on an informatics-enabled clinical research workflow, integration across heterogeneous data sources, and core informatics tools and platforms. We use this conceptual model to highlight 18 new articles in the JAMIA special issue on clinical research informatics.

PubMed Disclaimer

Conflict of interest statement

Competing interests: None.

Figures

Figure 1
Figure 1
A conceptual model for clinical research informatics consisting of an informatics-enabled clinical research workflow, heterogeneous data sources, and a collection of informatics methods and platforms. EHR, electronic health records; IDR, integrated data repositories; PHR, personal health records.
See this image and copyright information in PMC

References

    1. Embi PJ, Payne PR. Clinical research informatics: challenges, opportunities and definition for an emerging domain. J Am Med Inform Assoc 2009;16:316–27 - PMC - PubMed
    1. Payne PR, Embi PJ, Sen CK. Translational informatics: enabling high-throughput research paradigms. Physiol Genomics 2009;39:131–40 - PMC - PubMed
    1. Westfall JM, Mold J, Fagnan L. Practice-based research–“Blue Highways” on the NIH roadmap. JAMA 2007;297:403–6 - PubMed
    1. Dilts DM, Rosenblum D, Trochim WM. A virtual national laboratory for reengineering clinical translational science. Sci Transl Med 2012;4:118cm2 - PMC - PubMed
    1. Zerhouni EA, Alving B. Clinical and translational science awards: a framework for a national research agenda. Transl Res 2006;148:4–5 - PubMed

Publication types